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Critical Care Medicine January 2020

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

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Mirjana Jerkic, M.D., Ph.D.; Stéphane Gagnon, M.Sc.; Razieh Rabani, B.Sc., Ph.D.; Taylor Ward-Able, B.Sc.; Claire Masterson, M.Sc., Ph.D.; Gail Otulakowski, B.Sc., Ph.D.; Gerard F. Curley, M.B., Ph.D., F.C.A.I.; John Marshall, M.D., F.R.C.S.C., F.A.C.S., F.C.A.H.S.; Brian P. Kavanagh, M.D.; John G. Laffey, M.D., M.A., F.C.A.I.
TOPICS: heme, oxygenases, sepsis, stem cell, mesenchymal, umbilical cord, macrophages, macrophages, peritoneal, killing, rats
Anesthesiology. 2020; 132(1):140-154. doi: https://doi.org/10.1097/ALN.0000000000003018

Education September 2019

Imaging the Injured Lung: Mechanisms of Action and Clinical Use

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Alberto Goffi, M.D.; Jacob Herrmann, Ph.D.; David W. Kaczka, M.D., Ph.D.; Brian P. Kavanagh, M.D.; Gaetano Perchiazzi, M.D., Ph.D.; Takeshi Yoshida, M.D., Ph.D.; Rahim R. Rizi, Ph.D.
TOPICS: computed tomography, diagnostic imaging, lung, respiratory distress syndrome, adult, magnetic resonance imaging, respiration
Anesthesiology. 2019; 131(3):716-749. doi: https://doi.org/10.1097/ALN.0000000000002583

Critical Care Medicine September 2019

Driving Pressure Is Associated with Outcome during Assisted Ventilation in Acute Respiratory Distress Syndrome

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Giacomo Bellani, M.D., Ph.D.; Alice Grassi, M.D.; Simone Sosio, M.D.; Stefano Gatti, M.D.; Brian P. Kavanagh, M.B.; Antonio Pesenti, M.D.; Giuseppe Foti, M.D.
TOPICS: environmental air flow, plateau pressure, respiration, respiratory distress syndrome, adult, lung compliance, controlled ventilation
Anesthesiology. 2019; 131(3):594-604. doi: https://doi.org/10.1097/ALN.0000000000002846

Critical Care Medicine July 2018

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

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Gail Otulakowski, Ph.D.; Doreen Engelberts, A.H.T.; Martin Post, Ph.D.; Claire Masterson, Ph.D.; Brian P. Kavanagh, M.B., M.R.C.P.(I), F.R.C.P.(C)
TOPICS: desensitization, endothelial cells, lung, mechanical ventilation, mice, receptor protein-tyrosine kinases, signal transduction
Anesthesiology. 2018; 129(1):143-153. doi: https://doi.org/10.1097/ALN.0000000000002140

Critical Care Medicine July 2018

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

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Takeshi Yoshida, M.D., Ph.D.; Doreen Engelberts; Gail Otulakowski, Ph.D.; Bhushan Katira, M.D.; Martin Post, Ph.D.; Niall D. Ferguson, M.D.; Laurent Brochard, M.D., Ph.D.; Marcelo B. P. Amato, M.D., Ph.D.; Brian P. Kavanagh, M.B.
TOPICS: abdomen, lung, lung injury, ventilator-associated, positive end-expiratory pressure, suidae, lung injuries, respiration
Anesthesiology. 2018; 129(1):163-172. doi: https://doi.org/10.1097/ALN.0000000000002236

Critical Care Medicine January 2016

Visualizing the Propagation of Acute Lung Injury

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Natalie Meeder, B.A.; Johnathan Zeng, B.S.E.; YunQing Jiang, M.S.E.; Hooman Hamedani, M.S.; Harrilla Profka, D.V.M.; Stephen Kadlecek, Ph.D.; Justin Clapp, Ph.D.; Charuhas G. Deshpande, M.D.; Jue Wu, Ph.D.; James C. Gee, Ph.D.; Brian P. Kavanagh, M.B.; Rahim R. Rizi, Ph.D.
TOPICS: acute lung injury, computed tomography, environmental air flow, inspiration, lung, lung injuries, rats, respiration, aspirations (psychology), endotracheal aspiration
Anesthesiology. 2016; 124(1):121-131. doi: https://doi.org/10.1097/ALN.0000000000000916

Special Announcements October 2015

Journal-related Activities and Other Special Activities at the 2015 American Society of Anesthesiologists Annual Meeting

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J. David Clark, M.D., Ph.D.; Brian P. Kavanagh, M.B., F.R.C.P.C.; Piyush M. Patel, M.D., F.R.C.P.C.; James P. Rathmell, M.D.; Warren S. Sandberg, M.D., Ph.D.

Anesthesiology. 2015; 123(4):750-758. doi: https://doi.org/10.1097/ALN.0000000000000843

Editorial Views August 2015

Anesthetics and Lung Injury: Old Research, New Insights

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Brian P. Kavanagh, M.B., F.R.C.P.C.; Gail Otulakowski, Ph.D.
TOPICS: lung injuries, isoflurane
Anesthesiology. 2015; 123(2):251-252. doi: https://doi.org/10.1097/ALN.0000000000000743

Critical Care Medicine April 2015

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

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Christopher Yildiz, M.Sc.; Nades Palaniyar, M.Sc., Ph.D.; Gail Otulakowski, Ph.D.; Meraj A. Khan, M.Sc., Ph.D.; Martin Post, Ph.D.; Wolfgang M. Kuebler, M.D.; Keith Tanswell, M.B., M.R.C.P.(U.K.), F.R.C.P.(C.); Rosetta Belcastro, B.Sc.; Azhar Masood, M.D., Ph.D.; Doreen Engelberts, A.H.T.; Brian P. Kavanagh, M.B., M.R.C.P.(I.), F.R.C.P.(C.)
TOPICS: bronchoalveolar lavage fluid, deoxyribonuclease i, dna, lipopolysaccharides, lung, lung injuries, lung injury, ventilator-associated, mechanical ventilation, mice, neutrophils
Anesthesiology. 2015; 122(4):864-875. doi: https://doi.org/10.1097/ALN.0000000000000605

Correspondence February 2015

In Reply

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Neil M. Goldenberg, M.D., Ph.D.; Benjamin E. Steinberg, M.D., Ph.D.; Warren L. Lee, M.D., Ph.D., F.R.C.P.C.; Duminda N. Wijeysundera, M.D., Ph.D., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2015; 122(2):473-474. doi: https://doi.org/10.1097/ALN.0000000000000550

Education July 2014

Lung-protective Ventilation in the Operating Room: Time to Implement?

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Neil M. Goldenberg, M.D., Ph.D.; Benjamin E. Steinberg, M.D., Ph.D.; Warren L. Lee, M.D., Ph.D., F.R.C.P.C.; Duminda N. Wijeysundera, M.D., Ph.D., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.
TOPICS: environmental air flow, lung, operating room, respiration
Anesthesiology. 2014; 121(1):184-188. doi: https://doi.org/10.1097/ALN.0000000000000274

Critical Care Medicine December 2013

Positive End-expiratory Pressure Increments during Anesthesia in Normal Lung Result in Hysteresis and Greater Numbers of Smaller Aerated Airspaces

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Kiarash Emami, Ph.D.; Jessie Huang, B.S.; Jennia Rajaei, B.S.; Harrilla Profka, D.V.M.; Biao Han, M.S.; Puttisarn Mongkolwisetwara, M.S.; Stephen Kadlecek, Ph.D.; Nicholas N. Kuzma, Ph.D.; Stephen Pickup, Ph.D.; Brian P. Kavanagh, M.B.; Clifford S. Deutschman, M.D.; Rahim R. Rizi, Ph.D.
TOPICS: hysteresis, lung, positive end-expiratory pressure, wheelchair ramps, lung volume
Anesthesiology. 2013; 119(6):1402-1409. doi: https://doi.org/10.1097/ALN.0b013e3182a9b0c1

Editorial Views September 2012

Ventilator-induced Diaphragm Dysfunction: From Mice (Hopefully) to Men

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Ewan C. Goligher, M.D., F.R.C.P.(C); Niall D. Ferguson, M.D., M.Sc., F.R.C.P.(C); Brian P. Kavanagh, M.B., F.R.C.P.(C)
TOPICS: mice, ventilator-induced diaphragm dysfunction
Anesthesiology. 2012; 117(3):463-464. doi: https://doi.org/10.1097/ALN.0b013e318261e81c

Editorial Views July 2010

Hydrogen Sulfide in Lung Injury: Therapeutic Hope from a Toxic Gas?

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Gail Otulakowski, Ph.D.; Brian P. Kavanagh, M.B., F.R.C.P.C., F.C.A.R.C.S.I.
TOPICS: hydrogen sulfide, lung injuries
Anesthesiology. 2010; 113(1):4-6. doi: https://doi.org/10.1097/ALN.0b013e3181dec00e

Correspondence July 2009

Is Faculty Presence during Emergent Tracheal Intubations Justified?

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2009; 111(1):218. doi: https://doi.org/10.1097/ALN.0b013e3181a99961

Editorial Views December 2008

Emergency Airway Management: Competence versusExpertise?

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.
TOPICS: airway maintenance, competence
Anesthesiology. 2008; 109(6):945-947. doi: https://doi.org/10.1097/ALN.0b013e31818e3f8f

Correspondence October 2008

The Name of the Game: No Transfusion (or Nontransfusion) by Cookbook

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2008; 109(4):745-746. doi: https://doi.org/10.1097/ALN.0b013e31818631d4

Meeting Abstracts June 2008

Vascular Remodeling Protects against Ventilator-induced Lung Injury in the In Vivo Rat

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Alik Kornecki, M.D.; Doreen Engelberts, A.H.T.; Patrick McNamara, M.B.; Robert P. Jankov, M.D.; Conán McCaul, M.B.; Cameron Ackerley, Ph.D.; Martin Post, Ph.D.; Brian P. Kavanagh, M.B.

Anesthesiology. 2008; 108(6):1047-1054. doi: https://doi.org/10.1097/ALN.0b013e318173ed20

Meeting Abstracts September 2005

Oxygen Attenuates Atelectasis-induced Injury in the In Vivo Rat Lung

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Michelle Duggan, M.D.; Patrick J. McNamara, M.D.; Doreen Engelberts; Cecil Pace-Asciak, M.D.; Paul Babyn, M.D.; Martin Post, Ph.D.; Brian P. Kavanagh, M.D.

Anesthesiology. 2005; 103(3):522-531. doi:

Review Article April 2005

Pulmonary Atelectasis: A Pathogenic Perioperative Entity

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Michelle Duggan, M.B.; Brian P. Kavanagh, M.B.
TOPICS: atelectasis, lung
Anesthesiology. 2005; 102(4):838-854. doi:

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Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

Imaging the Injured Lung: Mechanisms of Action and Clinical Use

Driving Pressure Is Associated with Outcome during Assisted Ventilation in Acute Respiratory Distress Syndrome

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

Visualizing the Propagation of Acute Lung Injury

Journal-related Activities and Other Special Activities at the 2015 American Society of Anesthesiologists Annual Meeting

Anesthetics and Lung Injury: Old Research, New Insights

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

In Reply

Lung-protective Ventilation in the Operating Room: Time to Implement?

Positive End-expiratory Pressure Increments during Anesthesia in Normal Lung Result in Hysteresis and Greater Numbers of Smaller Aerated Airspaces

Ventilator-induced Diaphragm Dysfunction: From Mice (Hopefully) to Men

Hydrogen Sulfide in Lung Injury: Therapeutic Hope from a Toxic Gas?

Is Faculty Presence during Emergent Tracheal Intubations Justified?

Emergency Airway Management: Competence versusExpertise?

The Name of the Game: No Transfusion (or Nontransfusion) by Cookbook

Vascular Remodeling Protects against Ventilator-induced Lung Injury in the In Vivo Rat

Oxygen Attenuates Atelectasis-induced Injury in the In Vivo Rat Lung

Pulmonary Atelectasis: A Pathogenic Perioperative Entity

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