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Critical Care Medicine January 2020

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

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Mirjana Jerkic, M.D., Ph.D.; Stéphane Gagnon, M.Sc.; Razieh Rabani, B.Sc., Ph.D.; Taylor Ward-Able, B.Sc.; Claire Masterson, M.Sc., Ph.D.; Gail Otulakowski, B.Sc., Ph.D.; Gerard F. Curley, M.B., Ph.D., F.C.A.I.; John Marshall, M.D., F.R.C.S.C., F.A.C.S., F.C.A.H.S.; Brian P. Kavanagh, M.D.; John G. Laffey, M.D., M.A., F.C.A.I.
TOPICS: heme, oxygenases, sepsis, stem cell, mesenchymal, umbilical cord, macrophages, macrophages, peritoneal, killing, rats
Anesthesiology. 2020; 132(1):140-154. doi: https://doi.org/10.1097/ALN.0000000000003018

Critical Care Medicine September 2019

Driving Pressure Is Associated with Outcome during Assisted Ventilation in Acute Respiratory Distress Syndrome

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Giacomo Bellani, M.D., Ph.D.; Alice Grassi, M.D.; Simone Sosio, M.D.; Stefano Gatti, M.D.; Brian P. Kavanagh, M.B.; Antonio Pesenti, M.D.; Giuseppe Foti, M.D.
TOPICS: environmental air flow, plateau pressure, respiration, respiratory distress syndrome, adult, lung compliance, controlled ventilation
Anesthesiology. 2019; 131(3):594-604. doi: https://doi.org/10.1097/ALN.0000000000002846

Education September 2019

Imaging the Injured Lung: Mechanisms of Action and Clinical Use

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Alberto Goffi, M.D.; Jacob Herrmann, Ph.D.; David W. Kaczka, M.D., Ph.D.; Brian P. Kavanagh, M.D.; Gaetano Perchiazzi, M.D., Ph.D.; Takeshi Yoshida, M.D., Ph.D.; Rahim R. Rizi, Ph.D.
TOPICS: computed tomography, diagnostic imaging, lung, respiratory distress syndrome, adult, magnetic resonance imaging, respiration
Anesthesiology. 2019; 131(3):716-749. doi: https://doi.org/10.1097/ALN.0000000000002583

Critical Care Medicine July 2018

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

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Gail Otulakowski, Ph.D.; Doreen Engelberts, A.H.T.; Martin Post, Ph.D.; Claire Masterson, Ph.D.; Brian P. Kavanagh, M.B., M.R.C.P.(I), F.R.C.P.(C)
TOPICS: signal transduction, endothelial cells, lung, receptor protein-tyrosine kinases, mice, desensitization, mechanical ventilation
Anesthesiology. 2018; 129(1):143-153. doi: https://doi.org/10.1097/ALN.0000000000002140

Critical Care Medicine July 2018

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

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Takeshi Yoshida, M.D., Ph.D.; Doreen Engelberts; Gail Otulakowski, Ph.D.; Bhushan Katira, M.D.; Martin Post, Ph.D.; Niall D. Ferguson, M.D.; Laurent Brochard, M.D., Ph.D.; Marcelo B. P. Amato, M.D., Ph.D.; Brian P. Kavanagh, M.B.
TOPICS: respiration, lung, positive end-expiratory pressure, suidae, abdomen, lung injury, ventilator-associated, lung injuries
Anesthesiology. 2018; 129(1):163-172. doi: https://doi.org/10.1097/ALN.0000000000002236

Critical Care Medicine January 2016

Visualizing the Propagation of Acute Lung Injury

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Natalie Meeder, B.A.; Johnathan Zeng, B.S.E.; YunQing Jiang, M.S.E.; Hooman Hamedani, M.S.; Harrilla Profka, D.V.M.; Stephen Kadlecek, Ph.D.; Justin Clapp, Ph.D.; Charuhas G. Deshpande, M.D.; Jue Wu, Ph.D.; James C. Gee, Ph.D.; Brian P. Kavanagh, M.B.; Rahim R. Rizi, Ph.D.
TOPICS: respiration, acute lung injury, computed tomography, lung, inspiration, aspirations (psychology), endotracheal aspiration, pulmonary aspiration, rats, environmental air flow
Anesthesiology. 2016; 124(1):121-131. doi: https://doi.org/10.1097/ALN.0000000000000916

Special Announcements October 2015

Journal-related Activities and Other Special Activities at the 2015 American Society of Anesthesiologists Annual Meeting

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J. David Clark, M.D., Ph.D.; Brian P. Kavanagh, M.B., F.R.C.P.C.; Piyush M. Patel, M.D., F.R.C.P.C.; James P. Rathmell, M.D.; Warren S. Sandberg, M.D., Ph.D.

Anesthesiology. 2015; 123(4):750-758. doi: https://doi.org/10.1097/ALN.0000000000000843

Editorial Views August 2015

Anesthetics and Lung Injury: Old Research, New Insights

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Brian P. Kavanagh, M.B., F.R.C.P.C.; Gail Otulakowski, Ph.D.
TOPICS: isoflurane, lung injuries
Anesthesiology. 2015; 123(2):251-252. doi: https://doi.org/10.1097/ALN.0000000000000743

Critical Care Medicine April 2015

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

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Christopher Yildiz, M.Sc.; Nades Palaniyar, M.Sc., Ph.D.; Gail Otulakowski, Ph.D.; Meraj A. Khan, M.Sc., Ph.D.; Martin Post, Ph.D.; Wolfgang M. Kuebler, M.D.; Keith Tanswell, M.B., M.R.C.P.(U.K.), F.R.C.P.(C.); Rosetta Belcastro, B.Sc.; Azhar Masood, M.D., Ph.D.; Doreen Engelberts, A.H.T.; Brian P. Kavanagh, M.B., M.R.C.P.(I.), F.R.C.P.(C.)
TOPICS: respiration, lung, bronchoalveolar lavage fluid, cd40 ligand, deoxyribonuclease i, deoxyribonucleases, dna, hmgb1 protein, lipopolysaccharides, neutrophils
Anesthesiology. 2015; 122(4):864-875. doi: https://doi.org/10.1097/ALN.0000000000000605

Correspondence February 2015

In Reply

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Neil M. Goldenberg, M.D., Ph.D.; Benjamin E. Steinberg, M.D., Ph.D.; Warren L. Lee, M.D., Ph.D., F.R.C.P.C.; Duminda N. Wijeysundera, M.D., Ph.D., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2015; 122(2):473-474. doi: https://doi.org/10.1097/ALN.0000000000000550

Education July 2014

Lung-protective Ventilation in the Operating Room: Time to Implement?

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Neil M. Goldenberg, M.D., Ph.D.; Benjamin E. Steinberg, M.D., Ph.D.; Warren L. Lee, M.D., Ph.D., F.R.C.P.C.; Duminda N. Wijeysundera, M.D., Ph.D., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.
TOPICS: respiration, lung, operating room, environmental air flow
Anesthesiology. 2014; 121(1):184-188. doi: https://doi.org/10.1097/ALN.0000000000000274

Critical Care Medicine December 2013

Positive End-expiratory Pressure Increments during Anesthesia in Normal Lung Result in Hysteresis and Greater Numbers of Smaller Aerated Airspaces

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Maurizio Cereda, M.D.; Yi Xin, M.S.; Kiarash Emami, Ph.D.; Jessie Huang, B.S.; Jennia Rajaei, B.S.; Harrilla Profka, D.V.M.; Biao Han, M.S.; Puttisarn Mongkolwisetwara, M.S.; Stephen Kadlecek, Ph.D.; Nicholas N. Kuzma, Ph.D.; Stephen Pickup, Ph.D.; Brian P. Kavanagh, M.B.; Clifford S. Deutschman, M.D.; Rahim R. Rizi, Ph.D.
TOPICS: lung, positive end-expiratory pressure, lung volume, hysteresis, wheelchair ramps
Anesthesiology. 2013; 119(6):1402-1409. doi: https://doi.org/10.1097/ALN.0b013e3182a9b0c1

Editorial Views September 2012

Ventilator-induced Diaphragm Dysfunction: From Mice (Hopefully) to Men

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Ewan C. Goligher, M.D., F.R.C.P.(C); Niall D. Ferguson, M.D., M.Sc., F.R.C.P.(C); Brian P. Kavanagh, M.B., F.R.C.P.(C)
TOPICS: mice, ventilator-induced diaphragm dysfunction
Anesthesiology. 2012; 117(3):463-464. doi: https://doi.org/10.1097/ALN.0b013e318261e81c

Editorial Views July 2010

Hydrogen Sulfide in Lung Injury: Therapeutic Hope from a Toxic Gas?

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Gail Otulakowski, Ph.D.; Brian P. Kavanagh, M.B., F.R.C.P.C., F.C.A.R.C.S.I.
TOPICS: hydrogen sulfide, lung injuries
Anesthesiology. 2010; 113(1):4-6. doi: https://doi.org/10.1097/ALN.0b013e3181dec00e

Correspondence July 2009

Is Faculty Presence during Emergent Tracheal Intubations Justified?

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2009; 111(1):218. doi: https://doi.org/10.1097/ALN.0b013e3181a99961

Editorial Views December 2008

Emergency Airway Management: Competence versusExpertise?

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.
TOPICS: competence, airway maintenance
Anesthesiology. 2008; 109(6):945-947. doi: https://doi.org/10.1097/ALN.0b013e31818e3f8f

Correspondence October 2008

The Name of the Game: No Transfusion (or Nontransfusion) by Cookbook

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John F. Boylan, M.B., F.R.C.P.C.; Brian P. Kavanagh, M.B., F.R.C.P.C.

Anesthesiology. 2008; 109(4):745-746. doi: https://doi.org/10.1097/ALN.0b013e31818631d4

Meeting Abstracts June 2008

Vascular Remodeling Protects against Ventilator-induced Lung Injury in the In Vivo Rat

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Alik Kornecki, M.D.; Doreen Engelberts, A.H.T.; Patrick McNamara, M.B.; Robert P. Jankov, M.D.; Conán McCaul, M.B.; Cameron Ackerley, Ph.D.; Martin Post, Ph.D.; Brian P. Kavanagh, M.B.

Anesthesiology. 2008; 108(6):1047-1054. doi: https://doi.org/10.1097/ALN.0b013e318173ed20

Meeting Abstracts September 2005

Oxygen Attenuates Atelectasis-induced Injury in the In Vivo Rat Lung

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Michelle Duggan, M.D.; Patrick J. McNamara, M.D.; Doreen Engelberts; Cecil Pace-Asciak, M.D.; Paul Babyn, M.D.; Martin Post, Ph.D.; Brian P. Kavanagh, M.D.

Anesthesiology. 2005; 103(3):522-531. doi: https://doi.org/

Review Article April 2005

Pulmonary Atelectasis: A Pathogenic Perioperative Entity

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Michelle Duggan, M.B.; Brian P. Kavanagh, M.B.
TOPICS: lung, atelectasis
Anesthesiology. 2005; 102(4):838-854. doi: https://doi.org/

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Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats

Driving Pressure Is Associated with Outcome during Assisted Ventilation in Acute Respiratory Distress Syndrome

Imaging the Injured Lung: Mechanisms of Action and Clinical Use

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model

Visualizing the Propagation of Acute Lung Injury

Journal-related Activities and Other Special Activities at the 2015 American Society of Anesthesiologists Annual Meeting

Anesthetics and Lung Injury: Old Research, New Insights

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

In Reply

Lung-protective Ventilation in the Operating Room: Time to Implement?

Positive End-expiratory Pressure Increments during Anesthesia in Normal Lung Result in Hysteresis and Greater Numbers of Smaller Aerated Airspaces

Ventilator-induced Diaphragm Dysfunction: From Mice (Hopefully) to Men

Hydrogen Sulfide in Lung Injury: Therapeutic Hope from a Toxic Gas?

Is Faculty Presence during Emergent Tracheal Intubations Justified?

Emergency Airway Management: Competence versusExpertise?

The Name of the Game: No Transfusion (or Nontransfusion) by Cookbook

Vascular Remodeling Protects against Ventilator-induced Lung Injury in the In Vivo Rat

Oxygen Attenuates Atelectasis-induced Injury in the In Vivo Rat Lung

Pulmonary Atelectasis: A Pathogenic Perioperative Entity

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