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Prediction of Postoperative Pain: A Systematic Review of Predictive Experimental Pain Studies Free
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Mads U. Werner, M.D., D.M.Sc.; Helena N. Mjöbo, M.D.; Per R. Nielsen, M.D.; Åsa Rudin, M.D., Ph.D.
Tags: pain, postoperative pain, preoperative care, surgical procedures, operative, healthcare quality assessment
Anesthesiology June 2010, Vol.112, 1494-1502. doi:https://doi.org/10.1097/ALN.0b013e3181dcd5a0
Cellular Effects of Helium in Different Organs Free
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Gezina T.M.L. Oei, B.Sc., M.Sc.; Nina C. Weber, Ph.D.; Markus W. Hollmann, M.D., Ph.D., D.E.A.A.; Benedikt Preckel, M.D., M.A., D.E.A.A.
Tags: helium
Anesthesiology June 2010, Vol.112, 1503-1510. doi:https://doi.org/10.1097/ALN.0b013e3181d9cb5e

This Month in Anesthesiology

THIS MONTH IN Anesthesiology  Free
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Anesthesiology June 2010, Vol.112, 9A. doi:https://doi.org/10.1097/01.anes.0000376903.66213.52

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit Free
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Anesthesiology June 2010, Vol.112, A13. doi:https://doi.org/10.1097/01.anes.0000376904.04332.2b

Editorial

Anesthesiology and the Japanese Society of Anesthesiologists: The Science Is Amazing Free
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James C. Eisenach, M.D.; Koji Sumikawa, M.D., Ph.D.; Tetsuji Makita, M.D., Ph.D.; Sungsam Cho, M.D.
Tags: pain, schools, medical, biological markers, brain, care of intensive care unit patient
Anesthesiology June 2010, Vol.112, 1301-1302. doi:https://doi.org/10.1097/ALN.0b013e3181de0e8d
Diastolic Function: A Barometer for Cardiovascular Risk? Free
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Leanne Groban, M.D.; Dalane W. Kitzman, M.D.
Tags: cardiovascular disease risk factors, diastole
Anesthesiology June 2010, Vol.112, 1303-1306. doi:https://doi.org/10.1097/ALN.0b013e3181da89e4
Are Copy Number Variants of Defensins a Key Source of Variation in the Orchestrated Response to Infection? Free
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James A. Russell, M.D.
Tags: copy number polymorphism, defensins, infection
Anesthesiology June 2010, Vol.112, 1307-1308. doi:https://doi.org/10.1097/ALN.0b013e3181d96909
Wasabi and a Volatile Anesthetic Free
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George Gallos, M.D.; Pamela Flood, M.D.
Tags: volatile anesthetics
Anesthesiology June 2010, Vol.112, 1309-1310. doi:https://doi.org/10.1097/ALN.0b013e3181d94e1b
Predicting Postoperative Pain Based on Preoperative Pain Perception: Are We Doing Better Than the Weatherman? Free
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Srinivasa N. Raja, M.D.; Troels S. Jensen, M.D., Ph.D.
Tags: pain perception, postoperative pain, preoperative care, pain
Anesthesiology June 2010, Vol.112, 1311-1312. doi:https://doi.org/10.1097/ALN.0b013e3181dcd5cc

Special Announcements

Journal Symposium at the Japanese Society of Anesthesiologists Annual Meeting: Outcomes Beyond the Operating Room Free
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Daniel I. Sessler, M.D.; Makoto Ozaki, M.D.
Anesthesiology June 2010, Vol.112, 1313-1315. doi:https://doi.org/10.1097/ALN.0b013e3181de35cd

Perioperative Medicine

Prognostic Implications of Asymptomatic Left Ventricular Dysfunction in Patients Undergoing Vascular Surgery Free
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Willem-Jan Flu, M.D.; Jan-Peter van Kuijk, M.D.; Sanne E. Hoeks, Ph.D.; Ruud Kuiper, M.D.; Olaf Schouten, M.D.; Dustin Goei, M.D.; Abdou Elhendy, M.D.; Hence J. M. Verhagen, M.D.; Ian R. Thomson, M.D.; Jeroen J. Bax, M.D.; Lee A. Fleisher, M.D.; Don Poldermans, M.D.
Tags: vascular surgical procedures, ventricular dysfunction, left, surgical procedures, operative, heart failure
Anesthesiology June 2010, Vol.112, 1316-1324. doi:https://doi.org/10.1097/ALN.0b013e3181da89ca
Isoflurane Causes Greater Neurodegeneration Than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice Free
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Ge Liang, M.D.; Christopher Ward, M.D.; Jun Peng, M.D.; Yifan Zhao, M.D.; Baosheng Huang, M.D.; Huafeng Wei, M.D., Ph.D.
Tags: brain, isoflurane, mice, nerve degeneration, newborn
Anesthesiology June 2010, Vol.112, 1325-1334. doi:https://doi.org/10.1097/ALN.0b013e3181d94da5
Propofol Preferentially Relaxes Neurokinin Receptor-2-induced Airway Smooth Muscle Contraction in Guinea Pig Trachea Free
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Neil R. Gleason, M.D.; George Gallos, M.D.; Yi Zhang, M.D.; Charles W. Emala, M.D.
Tags: airway device, guinea, muscle, smooth, propofol, trachea
Anesthesiology June 2010, Vol.112, 1335-1344. doi:https://doi.org/10.1097/ALN.0b013e3181d3d7f6

Anesthesiology Reflections from the Wood Library-Museum

Gwathmey's 1914 Anesthesia Free
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George S. Bause, M.D., M.P.H.
Anesthesiology June 2010, Vol.112, 1344. doi:https://doi.org/10.1097/01.anes.0000376898.73837.8e

Perioperative Medicine

Detrusor Activity Is Impaired during Thoracic Epidural Analgesia after Open Renal Surgery Free
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Patrick Y. Wuethrich, M.D.; Thomas M. Kessler, M.D.; Jalesh N. Panicker, M.D., D.M., M.R.C.P. (UK); Michele Curatolo, M.D., Ph.D.; Fiona C. Burkhard, M.D.
Tags: local anesthetic thoracic epidural block, pain management, procedures on kidney, lower urinary tract
Anesthesiology June 2010, Vol.112, 1345-1349. doi:https://doi.org/10.1097/ALN.0b013e3181d4f4fe
Functional Studies of RYR1  Mutations in the Skeletal Muscle Ryanodine Receptor Using Human RYR1  Complementary DNA Free
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Keisaku Sato, M.Sc.; Neil Pollock, M.B.Ch.B.; Kathryn M. Stowell, Ph.D.
Tags: dna, complementary, mutation, ryr1, ryanodine receptor calcium release channel, skeletal muscles
Anesthesiology June 2010, Vol.112, 1350-1354. doi:https://doi.org/10.1097/ALN.0b013e3181d69283
Role of 70-kDa Ribosomal Protein S6 Kinase, Nitric Oxide Synthase, Glycogen Synthase Kinase-3β, and Mitochondrial Permeability Transition Pore in Desflurane-induced Postconditioning in Is... Free
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Sandrine Lemoine, Ph.D.; Lan Zhu, M.D., Ph.D.; Gallic Beauchef, Ph.D.; Olivier Lepage, M.D.; Gérard Babatasi, M.D., Ph.D.; Caline Ivascau, M.D.; Massimo Massetti, M.D., Ph.D.; Philippe Galera, Ph.D.; Jean-Louis Gérard, M.D., Ph.D.; Jean-Luc Hanouz, M.D., Ph.D.
Tags: atrium, desflurane, glycogen (starch) synthase, phosphotransferases, postconditioning, ischemic
Anesthesiology June 2010, Vol.112, 1355-1363. doi:https://doi.org/10.1097/ALN.0b013e3181d74f39
Susceptibility of Transcranial Electric Motor-evoked Potentials to Varying Targeted Blood Levels of Dexmedetomidine during Spine Surgery Free
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Mohamed Mahmoud, M.D.; Senthilkumar Sadhasivam, M.D., M.P.H.; Shelia Salisbury, Ph.D.; Todd G. Nick, Ph.D.; Beverly Schnell, Ph.D.; Anthony K. Sestokas, Ph.D., D.A.B.N.M.; Cheryl Wiggins, Au.D., D.A.B.N.M.; Paul Samuels, M.D.; Thomas Kabalin, M.D.; John McAuliffe, M.D., M.B.A.
Tags: dexmedetomidine, motor evoked potentials, transcranial electric motor evoked potential monitoring, spinal procedure, propofol
Anesthesiology June 2010, Vol.112, 1364-1373. doi:https://doi.org/10.1097/ALN.0b013e3181d74f55
Importance of Volume and Concentration for Ropivacaine Interscalene Block in Preventing Recovery Room Pain and Minimizing Motor Block after Shoulder Surgery Free
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Michael J. Fredrickson, F.A.N.Z.C.A.; Katherine R. Smith, M.Biostat.; Andrew C. Wong, F.A.N.Z.C.A.
Tags: brachial plexus block by interscalene approach, interscalene block technique, operative procedure on shoulder, pain, postoperative anesthesia care unit
Anesthesiology June 2010, Vol.112, 1374-1381. doi:https://doi.org/10.1097/ALN.0b013e3181d6929d
Modeling the Non–Steady State Respiratory Effects of Remifentanil in Awake and Propofol-sedated Healthy Volunteers Free
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Erik Olofsen, M.Sc.; Merel Boom, M.D.; Diederik Nieuwenhuijs, M.D., Ph.D.; Elise Sarton, M.D., Ph.D.; Luc Teppema, Ph.D.; Leon Aarts, M.D., Ph.D.; Albert Dahan, M.D., Ph.D.
Tags: propofol, remifentanil, respiration, steady state, apnea
Anesthesiology June 2010, Vol.112, 1382-1395. doi:https://doi.org/10.1097/ALN.0b013e3181d69087
Pharmacokinetics of Lidocaine, Bupivacaine, and Levobupivacaine in Plasma and Brain in Awake Rats Free
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Yuko Ikeda, M.D.; Yutaka Oda, M.D., Ph.D.; Taketo Nakamura, M.D., Ph.D.; Ryota Takahashi, M.D., Ph.D.; Wakako Miyake, M.D.; Ichiro Hase, M.D., Ph.D.; Akira Asada, M.D., Ph.D.
Tags: brain, bupivacaine, levobupivacaine, lidocaine, pharmacokinetics
Anesthesiology June 2010, Vol.112, 1396-1403. doi:https://doi.org/10.1097/ALN.0b013e3181d9cc54
Anesthetic Sevoflurane Causes Neurotoxicity Differently in Neonatal Naïve and Alzheimer Disease Transgenic Mice Free
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Yan Lu, M.D., Ph.D.; Xu Wu, M.D., Ph.D.; Yuanlin Dong, M.D., M.S.; Zhipeng Xu, M.D., Ph.D.; Yiying Zhang, M.D.; Zhongcong Xie, M.D., Ph.D.
Tags: brain, mice, mice, transgenic, newborn, sevoflurane
Anesthesiology June 2010, Vol.112, 1404-1416. doi:https://doi.org/10.1097/ALN.0b013e3181d94de1
Naloxone Reversal of Morphine- and Morphine-6-Glucuronide-induced Respiratory Depression in Healthy Volunteers: A Mechanism-based Pharmacokinetic–Pharmacodynamic Modeling Study Free
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Erik Olofsen, M.Sc.; Eveline van Dorp, M.D., Ph.D.; Luc Teppema, Ph.D.; Leon Aarts, M.D., Ph.D.; Terry W. Smith, Ph.D.; Albert Dahan, M.D., Ph.D.; Elise Sarton, M.D., Ph.D.
Tags: morphine, naloxone, pharmacodynamics, respiratory depression, respiration
Anesthesiology June 2010, Vol.112, 1417-1427. doi:https://doi.org/10.1097/ALN.0b013e3181d5e29d

Critical Care Medicine

Increased Genomic Copy Number of DEFA1/DEFA3  Is Associated with Susceptibility to Severe Sepsis in Chinese Han Population Free
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QiXing Chen, M.D.; Matthew Hakimi, M.Sc.; ShuiJing Wu, M.D.; Yue Jin, M.Sc.; BaoLi Cheng, M.D., Ph.D.; HaiHong Wang, M.D., Ph.D.; GuoHao Xie, M.D.; Tomas Ganz, M.D., Ph.D.; Rose M. Linzmeier, Ph.D.; XiangMing Fang, M.D.
Tags: genome, sepsis, severe
Anesthesiology June 2010, Vol.112, 1428-1434. doi:https://doi.org/10.1097/ALN.0b013e3181d968eb
Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet: An In Vivoand In VitroStudy Free
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Boris Jung, M.D.; Jean-Michel Constantin, M.D., Ph.D.; Nans Rossel, M.D.; Charlotte Le Goff, M.D.; Mustapha Sebbane, M.D.; Yannael Coisel, M.D.; Gerald Chanques, M.D.; Emmanuel Futier, M.D.; Gerald Hugon; Xavier Capdevila, M.D., Ph.D.; Basil Petrof, M.D., Ph.D.; Stefan Matecki, M.D., Ph.D.; Samir Jaber, M.D., Ph.D.
Tags: adaptive support ventilation, cytomegalovirus, cytomegalovirus infections, mechanical ventilation, respiratory diaphragm
Anesthesiology June 2010, Vol.112, 1435-1443. doi:https://doi.org/10.1097/ALN.0b013e3181d7b036
Effect of PSD-95/SAP90 and/or PSD-93/Chapsyn-110 Deficiency on the Minimum Alveolar Anesthetic Concentration of Halothane in Mice Free
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Feng Tao, M.D., Ph.D.; John Skinner, B.S.; Ya Yang, Ph.D.; Roger A. Johns, M.D., M.H.S.
Tags: depression, post-stroke, halothane, mice, minimum alveolar concentration
Anesthesiology June 2010, Vol.112, 1444-1451. doi:https://doi.org/10.1097/ALN.0b013e3181dcd3dc

Pain Medicine

Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction Free
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Helge Eilers, M.D.; Fiore Cattaruzza, Ph.D.; Romina Nassini, Ph.D.; Serena Materazzi, Ph.D.; Eunice Andre, Ph.D.; Catherine Chu, B.A.; Graeme S. Cottrell, Ph.D.; Mark Schumacher, Ph.D., M.D.; Pierangelo Geppetti, M.D.; Nigel W. Bunnett, Ph.D.
Tags: anesthetics, general, bronchoconstriction, hyperalgesia, irritants, isoflurane
Anesthesiology June 2010, Vol.112, 1452-1463. doi:https://doi.org/10.1097/ALN.0b013e3181d94e00

Anesthesiology Reflections from the Wood Library-Museum

The Morton House I  by Vandam Free
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George S. Bause, M.D., M.P.H.
Anesthesiology June 2010, Vol.112, 1463. doi:https://doi.org/10.1097/01.anes.0000376899.81460.cd

Pain Medicine

A Comparison of Change in the 0–10 Numeric Rating Scale to a Pain Relief Scale and Global Medication Performance Scale in a Short-term Clinical Trial of Breakthrough Pain Intensity Free
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John T. Farrar, M.D., Ph.D.; Rosemary C. Polomano, Ph.D., R.N., F.A.A.N.; Jesse A. Berlin, Sc.D.; Brian L. Strom, M.D., M.P.H.
Tags: breakthrough pain, pain, numeric pain scale
Anesthesiology June 2010, Vol.112, 1464-1472. doi:https://doi.org/10.1097/ALN.0b013e3181de0e6d
Long-term Effect of Sciatic Nerve Block with Slow-release Lidocaine in a Rat Model of Postoperative Pain Free
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Masaru Tobe, M.D.; Hideaki Obata, M.D., Ph.D.; Takashi Suto, M.D.; Hideaki Yokoo, M.D., Ph.D.; Yoichi Nakazato, M.D., Ph.D.; Yasuhiko Tabata, Ph.D., D.M.Sci., D.Pharm.; Shigeru Saito, M.D., Ph.D.
Tags: lidocaine, postoperative pain, sciatic nerve block
Anesthesiology June 2010, Vol.112, 1473-1481. doi:https://doi.org/10.1097/ALN.0b013e3181d4f66f
Gene Knockdown of the N  -Methyl-d-Aspartate Receptor NR1 Subunit with Subcutaneous Small Interfering RNA Reduces Inflammation-induced Nociception in Rats Free
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Ping-Heng Tan, M.D., Ph.D.; Yuan-Yi Chia, M.D.; Lok-Hi Chow, M.D., Ph.D.; Jieh-Jie Chen, M.D.; Lin-Cheng Yang, M.D.; Kuo-Chuan Hung, M.D.; Hung-Shu Chen, M.D.; Chien-Hung Kuo, M.D.
Tags: genes, rats, rna, small interfering, pain perception, inflammation
Anesthesiology June 2010, Vol.112, 1482-1493. doi:https://doi.org/10.1097/ALN.0b013e3181d69494

Education

Case Scenario: Anesthetic Implications of Restless Legs Syndrome Free
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Mathieu Raux, M.D., Ph.D.; Elias G. Karroum, M.D.; Isabelle Arnulf, M.D., Ph.D.
Tags: restless legs syndrome, leg, symptom aggravating factors, sleep, surgical procedures, operative
Anesthesiology June 2010, Vol.112, 1511-1517. doi:https://doi.org/10.1097/ALN.0b013e3181de2d66