Newly Published
Clinical Focus Review  |   February 2020
Patient Blood Management: Effectiveness and Future Potential
Author Notes
  • From the Institute of Anesthesiology, University of Zurich and University Hospital Zurich, Zurich, Switzerland (D.R.S.); the Department of Surgical Specialties, Biochemistry and Immunology, School of Medicine, University of Málaga, Málaga, Spain (M.M.); the Department of Anaesthesia and Intensive Care, Royal Papworth Hospital, Cambridge, United Kingdom (A.A.K.); the Departments of Anesthesiology and Critical Care, Duke University School of Medicine, Durham, North Carolina (J.H.L.); and the Department of Anesthesiology, Intensive Care Medicine and Pain Therapy University Hospital Frankfurt, Germany (K.Z.).
  • Submitted for publication August 30, 2019. Accepted for publication January 22, 2020.
    Submitted for publication August 30, 2019. Accepted for publication January 22, 2020.×
  • Correspondence: Address correspondence to Dr. Spahn: Institute of Anesthesiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland. donat.spahn@usz.ch. Information on purchasing reprints may be found at www.anesthesiology.org or on the masthead page at the beginning of this issue. Anesthesiology’s articles are made freely accessible to all readers, for personal use only, 6 months from the cover date of the issue.
Article Information
Cardiovascular Anesthesia / Coagulation and Transfusion / Endocrine and Metabolic Systems / Hematologic System / Clinical Focus Review
Clinical Focus Review   |   February 2020
Patient Blood Management: Effectiveness and Future Potential
Anesthesiology Newly Published on February 25, 2020. doi:https://doi.org/10.1097/ALN.0000000000003198
Anesthesiology Newly Published on February 25, 2020. doi:https://doi.org/10.1097/ALN.0000000000003198
Before major surgery, 30 to 40% of patients are anemic, an important consideration that is associated with increased erythrocyte transfusions, prolonged hospital length of stay, more frequent intensive care admissions, infections, and thromboembolic events, and mortality.1–4  Surgical bleeding contributes to anemia, increases transfusions, and independently increases mortality.5  In addition, transfusion of allogeneic blood products is associated with increased morbidity and mortality6 and increased costs, and allogeneic blood products are a limited resource6.6–8  Therefore, as a pragmatic solution, the concept of Patient Blood Management was developed and published in its preliminary form, first in the anesthesia literature as an editorial in Anesthesiology in 2008.9  The authors hypothesized that “Patient Blood Management will decrease the use of allogeneic erythrocyte transfusion and its cost and adverse sequelae significantly.” Currently, 12 yr later, we can conclude this is indeed the case.10–12