From the Department of Critical Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands (J.D., J.G.v.d.H., L.M.A.H.); Department of Critical Care Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada (C.A.S.); Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada (J.B.); and Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, Toronto, Ontario, Canada (C.A.S., J.B.).
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Supplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are available in both the HTML and PDF versions of this article. Links to the digital files are provided in the HTML text of this article on the Journal’s Web site (
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Submitted for publication September 15, 2014. Accepted for publication March 9, 2015.
Submitted for publication September 15, 2014. Accepted for publication March 9, 2015.
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Address correspondence to Dr. Heunks: Department of Critical Care Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Gelderland, Nijmegen, The Netherlands.
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