Correspondence  |   January 2015
Lung Ultrasonography for the Detection of Anesthesia-induced Lung Atelectasis
Author Notes
  • Centre Hospitalier de l’Université de Montréal, Montréal, Québec, Canada (M.G.).
  • (Accepted for publication September 18, 2014.)
    (Accepted for publication September 18, 2014.)×
Article Information
Correspondence   |   January 2015
Lung Ultrasonography for the Detection of Anesthesia-induced Lung Atelectasis
Anesthesiology 01 2015, Vol.122, 213-214. doi:
Anesthesiology 01 2015, Vol.122, 213-214. doi:
To the Editor:
We have read with great interest the article by Acosta et al.1  exploring the use of lung ultrasound as a mean to detect intraoperative atelectasis. However, despite their statement to the contrary, the occurrence of B lines in the setting of atelectasis has already been described by others. Although B lines were initially thought to originate from the interaction of the ultrasound beam with thickened subpleural interlobular septa found in alveolar-interstitial pathologies,2  recent work has challenged this hypothesis. In an elegant series of experiments, Soldati et al.3–5  have shown that B lines are observed when the ultrasound beam interacts at the pleural surface with lung tissue of a specific density. Although this can occur with the replacement of subpleural air by an ultrasound-conductive substance (e.g., water, pus, blood, and fibrous tissue), the withdrawal of air (e.g., resorption atelectasis) will also lead to the genesis of B lines. Demonstrating this last point, in an ex vivo animal model of graded atelectasis, B lines were observed in increasing numbers with increasing atelectasis. Pathologic examination of the excised lungs showed diffusely compressed alveoli mixed with sporadic areas of normally expanded distal air spaces.5 
The study by Acosta et al. comes at an interesting moment. The recent publication of two randomized controlled trials6,7  exploring the impact of intraoperative mechanical ventilation parameters on postoperative pulmonary complications has generated much interest.8  Although some have linked the negative results of the PROVHILO (PROtective Ventilation using HIgh versus LOw positive end-expiratory pressure) trial to a lack of regular recruitment maneuvers and a positive end-expiratory pressure set too high,9  others blame the use of inappropriately high tidal volumes in the control group for the positive results in the IMPROVE (Intraoperative PROtective VEntilation) trial.10  In the absence of imagery supporting claims of atelectasis or overdistention, the culprits usually blamed for the development of postoperative pulmonary complications, it is unlikely this question will be resolved before more data becomes available. Interestingly, recent anesthesiology literature has demonstrated the advantage of hemodynamic optimization11  championing the concept that individualization is preferable to a “one size fits all” approach. Likewise, individualization of mechanical ventilation parameters might be an interesting avenue to explore if we wish to decrease the occurrence of postoperative respiratory complications. This hypothesis is supported by spiral computed tomography studies reporting significant interpatient variability in the amount of atelectasis induced by general anesthesia.12,13  Therefore, we believe that bedside monitoring to detect lung atelectasis or overdistention is needed. Although magnetic resonance imaging and computed tomography fulfill this requirement, they cannot be used in an intraoperative setting except in specially designed operating rooms and could not realistically be repeated throughout a procedure. Because lung ultrasonography can be performed at the bedside and is devoid of any ionizing radiation, the present study by Acosta et al., although interesting in and of itself, is an important milestone toward establishing lung ultrasonography as a tool to optimize intraoperative mechanical ventilation parameters. Other investigators have described loss of aeration scales that have allowed the study of the therapeutic effects of antibiotics in ventilator-associated pneumonia,14  the effect of different levels of positive end-expiratory pressure in patients with acute respiratory distress syndrome on lung reexpansion15  and the detection of patients likely to fail extubation after a successful spontaneous breathing trial.16  Although not developed specifically for the diagnosis and monitoring of anesthesia-induced atelectasis, the use of these scales would have been an interesting addition to the study by Acosta et al. Whether to optimize intraoperative mechanical ventilation parameters or to assist anesthesiologists in the care of hypoxemic patients, lung ultrasonography is likely to have a bright future in our operating rooms.
Supported by Grant of the Fondation 2013, Fondation d’anesthésiologie et réanimation du Québec; Grant of the Fonds de développement 2014, Département d’anesthésiologie, Université de Montréal.
Competing Interests
The authors declare no competing interests.
Martin Girard, M.D., Vincent Généreux, M.D., Audrey Monastesse, M.D. Centre Hospitalier de l’Université de Montréal, Montréal, Québec, Canada (M.G.).
Acosta, CM, Maidana, GA, Jacovitti, D, Belaunzarán, A, Cereceda, S, Rae, E, Molina, A, Gonorazky, S, Bohm, SH, Tusman, G Accuracy of transthoracic lung ultrasound for diagnosing anesthesia-induced atelectasis in children.. Anesthesiology. (2014). 120 1370–9 [Article] [PubMed]
Lichtenstein, D, Mézière, G, Biderman, P, Gepner, A, Barré, O The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome.. Am J Respir Crit Care Med. (1997). 156 1640–6 [Article] [PubMed]
Soldati, G, Copetti, R, Sher, S Sonographic interstitial syndrome: The sound of lung water.. J Ultrasound Med. (2009). 28 163–74 [PubMed]
Soldati, G, Giunta, V, Sher, S, Melosi, F, Dini, C “Synthetic” comets: A new look at lung sonography.. Ultrasound Med Biol. (2011). 37 1762–70 [Article] [PubMed]
Soldati, G, Inchingolo, R, Smargiassi, A, Sher, S, Nenna, R, Inchingolo, CD, Valente, S Ex vivo lung sonography: Morphologic-ultrasound relationship.. Ultrasound Med Biol. (2012). 38 1169–79 [Article] [PubMed]
Futier, E, Constantin, JM, Paugam-Burtz, C, Pascal, J, Eurin, M, Neuschwander, A, Marret, E, Beaussier, M, Gutton, C, Lefrant, JY, Allaouchiche, B, Verzilli, D, Leone, M, De Jong, A, Bazin, JE, Pereira, B, Jaber, S IMPROVE Study Group, A trial of intraoperative low-tidal-volume ventilation in abdominal surgery.. N Engl J Med. (2013). 369 428–37 [Article] [PubMed]
The PROVE Network Investigators, for the Clinical Trial Network of the European Society of Anaesthesiology, High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): A multicentre randomised controlled trial.. Lancet. (2014). 384 495–503 [Article] [PubMed]
Goldenberg, NM, Steinberg, BE, Lee, WL, Wijeysundera, DN, Kavanagh, BP Lung-protective ventilation in the operating room: Time to implement?. Anesthesiology. (2014). 121 184–8 [Article] [PubMed]
Futier, E Positive end-expiratory pressure in surgery: Good or bad?. Lancet. (2014). 384 472–4 [Article] [PubMed]
Wanderer, JP, Blum, JM, Ehrenfeld, JM Intraoperative low-tidal-volume ventilation.. N Engl J Med. (2013). 369 1861 [Article] [PubMed]
Corcoran, T, Rhodes, JE, Clarke, S, Myles, PS, Ho, KM Perioperative fluid management strategies in major surgery: A stratified meta-analysis.. Anesth Analg. (2012). 114 640–51 [Article] [PubMed]
Andersson, LE, Bååth, M, Thörne, A, Aspelin, P, Odeberg-Wernerman, S Effect of carbon dioxide pneumoperitoneum on development of atelectasis during anesthesia, examined by spiral computed tomography.. Anesthesiology. (2005). 102 293–9 [Article] [PubMed]
Reinius, H, Jonsson, L, Gustafsson, S, Sundbom, M, Duvernoy, O, Pelosi, P, Hedenstierna, G, Fredén, F Prevention of atelectasis in morbidly obese patients during general anesthesia and paralysis: A computerized tomography study.. Anesthesiology. (2009). 111 979–87 [Article] [PubMed]
Bouhemad, B, Liu, ZH, Arbelot, C, Zhang, M, Ferarri, F, Le-Guen, M, Girard, M, Lu, Q, Rouby, JJ Ultrasound assessment of antibiotic-induced pulmonary reaeration in ventilator-associated pneumonia.. Crit Care Med. (2010). 38 84–92 [Article] [PubMed]
Bouhemad, B, Brisson, H, Le-Guen, M, Arbelot, C, Lu, Q, Rouby, JJ Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment.. Am J Respir Crit Care Med. (2011). 183 341–7 [Article] [PubMed]
Soummer, A, Perbet, S, Brisson, H, Arbelot, C, Constantin, JM, Lu, Q, Rouby, JJ Lung Ultrasound Study Group, Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*.. Crit Care Med. (2012). 40 2064–72 [Article] [PubMed]