Correspondence  |   April 2017
Lung-protective Role of Halogenated Anesthetics: Is It Time to Change This Hypothesis?
Author Notes
  • Gregorio Marañón University Hospital, Madrid, Spain (F.d.l.G.). galareyes24@gmail.com
  • (Accepted for publication November 6, 2016.)
    (Accepted for publication November 6, 2016.)×
Article Information
Correspondence
Correspondence   |   April 2017
Lung-protective Role of Halogenated Anesthetics: Is It Time to Change This Hypothesis?
Anesthesiology 4 2017, Vol.126, 756. doi:10.1097/ALN.0000000000001557
Anesthesiology 4 2017, Vol.126, 756. doi:10.1097/ALN.0000000000001557
We read with great interest the results of the multicenter randomized controlled trial by Beck-Schimmer et al.1  We congratulate the authors on performing the first study with sufficient statistical power to detect differences in outcomes between two anesthetic techniques in lung resection surgery. The authors used a recognized anesthetic agent (desflurane) with protective (antiinflammatory) lung effects during one-lung ventilation (OLV), although they did not measure perioperative biomarkers of inflammatory response. Most previous hypotheses proposed that this lung-protective role must affect postoperative outcome; however, the surprising results of the study by Beck-Schimmer et al.1  lead us to think that it is perhaps time to reevaluate these hypotheses.
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