Correspondence  |   August 2016
Missing Randomization …
Author Notes
  • Charing Cross Hospital and Imperial College, London, United Kingdom (J.P.). johnjpicard@gmail.com
  • (Accepted for publication March 28, 2016.)
    (Accepted for publication March 28, 2016.)×
Article Information
Correspondence
Correspondence   |   August 2016
Missing Randomization …
Anesthesiology 8 2016, Vol.125, 417-418. doi:10.1097/ALN.0000000000001174
Anesthesiology 8 2016, Vol.125, 417-418. doi:10.1097/ALN.0000000000001174
Wigmore et al.1  report “an association between volatile inhalational anesthesia (INHA) and a reduction in the long-term survival of cancer patients” and the hypothesis that “volatile inhalational agent in anesthesia may augment cancer cell growth.”
We have three criticisms of the link between the hypothesis and the presented data.
Wigmore et al. have touched on questions of immense clinical significance. But we are not yet convinced that their data and analysis have implications for clinicians outside their own hospital. We agree with them that prospective research, with randomization of TIVA versus INHA, is needed.
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