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Correspondence  |   June 2000
Jugular Bulb Hemoglobin Oxygen Saturation Is Not a Standard for Comparison with Cerebral Oximetry in Head Injury
Author Notes
  • Professor
  • Department of Neurological Surgery
  • University of Pittsburgh School of Medicine
  • Pittsburgh, Pennsylvania
  • nemoto@neuronet.pitt.edu
Article Information
Correspondence
Correspondence   |   June 2000
Jugular Bulb Hemoglobin Oxygen Saturation Is Not a Standard for Comparison with Cerebral Oximetry in Head Injury
Anesthesiology 6 2000, Vol.92, 1847. doi:
Anesthesiology 6 2000, Vol.92, 1847. doi:
To the Editor:
—Minassian et al.  1 studied the correlation between cerebral cortical oxyhemoglobin saturation and jugular bulb oxyhemoglobin saturation in patients with head injury, and concluded that, “ScO2assessed by NIRS does not adequately reflect changes in SvjO2in patients with severe head injury.” However, jugular bulb oximetry may not be an appropriate standard of cerebral oxygenation assessment in patients with head injury. The transverse sinuses are fed by both hemispheres. Jugular bulb oxyhemoglobin saturation may tell us little except if this value is low, in which case it would indicate cerebral ischemia or hypoxia. However, if the value is normal or high, one cannot be sure that a large part of the brain is not hypoxic or ischemic. The situation in global phenomena such as global cerebral ischemia, encephalopathies, and cardiopulmonary bypass may be different.
If one samples blood from the right jugular bulb and perfusion to the right hemisphere is completely arrested, which may occur with the use of a carotid clamp during carotid endarterectomy, the blood must come from the opposite hemisphere. If there is no perfusion to the brain, the blood will likely enter the catheter in a retrograde fashion. In addition, because the near-infrared spectroscopy (NIRS) is a regional measurement, what can the expectations be in head injury? There is also the problem of microvascular shunting, which is discussed in an excellent review by Ince and Sinaasappel 2 who used a combination of methods to demonstrate microvascular shunting in sepsis and shock.
We evaluated NIRS monitoring in the intensive care unit in children with head injury.4Fluctuations in intracranial pressure that were in phase with cerebral cortical oxygenation suggest a vasodilatory process. If these fluctuations are out of phase with cerebral cortical oxygenation, the development of edema and vascular compression is indicated. Cerebral oximetry, whether in the operating room or in the intensive care unit, necessitates thoughtful consideration of all physiologic factors. Where possible, one should try to understand the injury by viewing the computed tomography scan and noting where contusions and accumulations of fluid or blood and regions of infarction are located to avoid placement of the sensors over those areas. The sensor may be placed over the at-risk area of the brain and the progression or subsidence of the disease with therapy may be followed. The sensor may then be used to optimize temperature, arterial blood pressure, and other variables. Finally, spontaneous fluctuations in cerebral oxygen availability with fluctuations in arterial pressure can provide insight into the quality of cerebrovascular autoregulation in the brain region that is being examined.
References
Minassian AT, Porier N, Pierrot M, Menei P, Granry JC, Ursion M, Beydon L: Correlation between cerebral oxygen saturation measured by near-infrared spectroscopy and jugular oxygen saturation in patients with severe closed head injury. A nesthesiology 1999; 91:985–90Minassian, AT Porier, N Pierrot, M Menei, P Granry, JC Ursion, M Beydon, L
Ince C, Sinaasappel M: Microcirculatory oxygenation and shunting in sepsis and shock. Crit Care Med 1999; 27:1639–7Ince, C Sinaasappel, M