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Retraction  |   April 2010
Pharmacokinetics and Clinical Pharmacodynamics of the New Propofol Prodrug GPI 15715 in Volunteers: Retraction
Article Information
Retraction
Retraction   |   April 2010
Pharmacokinetics and Clinical Pharmacodynamics of the New Propofol Prodrug GPI 15715 in Volunteers: Retraction
Anesthesiology 4 2010, Vol.112, 1058. doi:10.1097/ALN.0b013e3181d64705
Anesthesiology 4 2010, Vol.112, 1058. doi:10.1097/ALN.0b013e3181d64705
An analytical propofol assay inaccuracy was discovered after initial studies on the pharmacokinetics/pharmacodynamics and tolerability of fospropofol had been published. This assay inaccuracy makes the measured propofol plasma concentrations in the following previously published studies unreliable, and therefore these articles are retracted in their entirety:
Reference 
Fechner J, Ihmsen H, Hatterscheid D, Schiessl C, Vornov JJ, Burak E, Schwilden H, Schüttler J: Pharmacokinetics and clinical pharmacodynamics of the new propofol prodrug GPI 15715 in volunteers. Anesthesiology 2003; 99:303–13