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Correspondence  |   April 2010
Rapid Eye Movement Sleep and General Anesthesia
Author Affiliations & Notes
  • Kate Leslie, M.B.B.S., M.D., M.Epi., F.A.N.Z.C.A.
    *
  • *Royal Melbourne Hospital, Parkville, Victoria, Australia. (Sleigh, Leslie)
Article Information
Correspondence
Correspondence   |   April 2010
Rapid Eye Movement Sleep and General Anesthesia
Anesthesiology 4 2010, Vol.112, 1053. doi:10.1097/ALN.0b013e3181d423e2
Anesthesiology 4 2010, Vol.112, 1053. doi:10.1097/ALN.0b013e3181d423e2
In Reply:
We thank Dr. Mashour for his interest in our article.1 It is hard to avoid getting entangled in semantic issues in this type of research. As Dr. Mashour has indicated, the problem with traditional heuristic definitions of sleep stage is that they are arbitrarily defined and lack a proper causal linkage with sleep functions. Thus, we are in favor of Dr. Mashour's term “protoconsciousness” to describe states of mentation associated with activation (depolarization) of the cerebral cortex, but which fall short of wakeful responsiveness to the external world. These states are usually indicated by the increased electroencephalographic and bispectral index values and are common during general anesthesia.
*Royal Melbourne Hospital, Parkville, Victoria, Australia.
Reference
Reference
Leslie K, Sleigh J, Paech MJ, Voss L, Lim CW, Sleigh C: Dreaming and electroencephalographic changes during anesthesia maintained with propofol or desflurane. Anesthesiology 2009; 111:547–55Leslie, K Sleigh, J Paech, MJ Voss, L Lim, CW Sleigh, C