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Correspondence  |   December 2006
Contrast Imaging while Breast-feeding
Author Affiliations & Notes
  • Andrea Albertin, M.D.
    *
  • *Vita-Salute University of Milan, IRCCS San Raffaele, Milan, Italy.
Article Information
Correspondence
Correspondence   |   December 2006
Contrast Imaging while Breast-feeding
Anesthesiology 12 2006, Vol.105, 1277. doi:
Anesthesiology 12 2006, Vol.105, 1277. doi:
In Reply:—
In our case report, we state that the magnetic resonance imaging scanning was performed without contrast because the patient was breast-feeding.1 As Camann and Stuebe wrote, current recommendations suggest that the use of radiographic contrast media is compatible with breast-feeding.2 
However, the informative sheet of all three contrast brands in use at our hospital state that breast-feeding is a relative contraindication to contrast medium use. One contrast medium producer recommends a 24-h suspension of breast-feeding for lactating women in case of contrast medium administration. Kubik-Huch et al.  3 have demonstrated that small amounts of radiographic contrast medium are excreted into human breast milk during lactation, but the amount transferred to a nursing infant orally is so small that the authors state that the recommendation of a 24-h suspension of breast-feeding for lactating women should be reconsidered.
The clinical relevance of contrast medium excretion into human breast milk is not known. But because magnetic resonance imaging scanning without contrast gave us a satisfactory diagnostic certainty, we decided not to expose the patient to an avoidable risk.
*Vita-Salute University of Milan, IRCCS San Raffaele, Milan, Italy.
References
Albertin A, Marchetti C, Mamo D, Poli D, Dedola E: Intracranial hypotension: A case of spontaneous arachnoid rupture in a parturient. Anesthesiology 2006; 104:609–10Albertin, A Marchetti, C Mamo, D Poli, D Dedola, E
Webb JA, Thomsen HS, Morkos SK, members of Contrast Media Safety Committee of European Society of Urogenital Radiology: The use of iodinated and gadolinium contrast media during pregnancy and lactation. Eur Radiol 2005; 15:1234–40Webb, JA Thomsen, HS Morkos, SK members of Contrast Media Safety Committee of European Society of Urogenital Radiology,
Kubik-Huch RA, Gottstein-Aalame NM, Frenzel T, Seifert B, Puchert E, Wittek S, Debatin JF: Gadopentetate dimeglumine excretion into human breast milk during lactation. Radiology 2000; 216:555–8Kubik-Huch, RA Gottstein-Aalame, NM Frenzel, T Seifert, B Puchert, E Wittek, S Debatin, JF